10. Gray Lady Down
9. Juggernaut
8. Sunshine
7. Das Boot
6. The Hitch-Hiker
5. Alamar
4. Captains Courageous
3. The General
2. Two-Lane Blacktop
1. Mad Max: Fury Road
Not a complete list, just the first ten to come to mind. I tried to stick to movies where the majority of the story takes place of the vehicle, which ruled out options like United 93, Wild Boys of the Road, Jaws, and Fitzcarraldo (Two-Lane Blacktop might be a stretch in that regard). I left off a couple more that I need to revisit (Stagecoach, The Hunt for Red October, Speed, etc.). Ships/submarines could probably be a completely separate list, as with spaceships.
edit: Knife in the Water probably belongs on there somewhere, possibly along with Death Proof, Night Train to Munich, The Train, and Gravity.
pixote