Isle of Dogs
I'm conflicted about the film (I think everything that isn't just the dogs and Atari is... sketchy at best), but I have a hard time seeing anyone but Desplat get my #1 in Score this year, and yes I know it's very early.
While I'm at it:
The Death of Stalin
Actor (Steve Buscemi)
Line : "How can you run and plot at the same time ?"
Dramatic Scene: House interrogation (and what follows)
Dramatic Scene: Mirroring