I read Satoshi Kon's farewell note today, after stumbling across it on my desktop. I saved it shortly after his passing, but didn't read it at the time (I think I knew that finding a nice quiet moment to read it would be best).
I don't think I could tell you the last time I openly wept as I did reading that note. Just trying to write about it is difficult. If you can find it, I strongly recommend reading it, provided you're prepared to be devastated. It's powerful in an astonishing way.