RIP Leslie Nielsen
Rumack: Captain, how soon can you land?
Captain Oveur: I can't tell.
Rumack: You can tell me. I'm a doctor.
Captain Oveur: No. I mean I'm just not sure.
Rumack: Well, can't you take a guess?
Captain Oveur: Well, not for another two hours.
Rumack: You can't take a guess for another two hours?
Just heard the news on tv. Very sad news
Rumack: Can you fly this plane, and land it?
Ted Striker: Surely you can't be serious.
Rumack: I am serious... and don't call me Shirley.
And again. If it's a good gag, you just run with it
Rumack: I won't deceive you, Mr. Striker. We're running out of time.
Ted Striker: Surely there must be something you can do.
Rumack: I'm doing everything I can... and stop calling me Shirley!
Mayor: Oh, Drebin. I don't want any trouble like you had last year on the south side. Understand? That's my policy.
Frank: Yes, well when I see five weirdo's dressed in togas stabbing a guy in the middle of the park in full view of a hundred people, I shoot the bastards, that's my policy.
Mayor: That was a Shakespeare in the park production of "Julius Caesar" you moron! You killed five actors, good ones!
I think Adam quoted this one in a FS episode from ages ago.