Actually, I think it's pretty much spoiler free, now that I think back on it. I do recall letting slip a couple Doctor Who ones (one that's barely a spoiler in the section, and another when discussing my pick for Best Quote). If you're worried though, you can get the mp4 version, which has chapter breaks so you can skip around to different sections, based on what you've seen. So, if you're behind on, say, Justified, you can skip that and listen to the rest.